Reciprocal Allosteric Modulation of Carbon Monoxide and Warfarin Binding to Ferrous Human Serum Heme-Albumin

Human serum albumin (HSA), the most abundant protein in human plasma, could be considered as a prototypic monomeric allosteric protein, since the ligand-dependent conformational adaptability of HSA spreads beyond the immediate proximity of the binding site(s). As a matter of fact, HSA is a major tra...

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Detalles Bibliográficos
Autores principales: Bocedi, Alessio, De Sanctis, Giampiero, Ciaccio, Chiara, Tundo, Grazia R., Di Masi, Alessandra, Fanali, Gabriella, Nicoletti, Francesco P., Fasano, Mauro, Smulevich, Giulietta, Ascenzi, Paolo, Coletta, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605432/
https://www.ncbi.nlm.nih.gov/pubmed/23555601
http://dx.doi.org/10.1371/journal.pone.0058842

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