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Molecular genetic tests for JAK2V617F, Exon12_JAK2 and MPLW515K/L are highly informative in the evaluation of patients suspected to have BCR-ABL1-negative myeloproliferative neoplasms
Polycythaemia vera (PV), essential thrombocythemia (ET) and idiopathic myelofibrosis (MF), are the most common myeloproliferative neoplasms (MPN) in patients without the BCR-ABL1 gene rearrangement. They are caused by clonal expansion of haematopoietic stem cells and share, as a diagnostic criterion...
Autores principales: | dos Santos, Marcos Tadeu, Mitne-Neto, Miguel, Miyashiro, Kozue, Chauffaille, Maria de Lourdes L Ferrari, Rizzatti, Edgar Gil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913116/ https://www.ncbi.nlm.nih.gov/pubmed/23986553 http://dx.doi.org/10.1136/jclinpath-2013-201822 |
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