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Characterizing monkeypox virus specific CD8+ T cell epitopes in rhesus macaques

To characterize T cell epitopes in monkeypox virus (MPXV) infected rhesus macaques, we utilized IFNγ Elispot assay to screen 400 predicted peptides from 20 MPXV proteins. Two peptides from the F8L protein, an analog of E9L protein in vaccinia, were found to elicit CD8+ T cell responses. Prediction a...

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Detalles Bibliográficos
Autores principales:	Song, Haifeng, Sidney, John, Wiseman, Roger W, Josleyn, Nicole, Cohen, Melanie, Blaney, Joseph E, Jahrling, Peter B, Sette, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. Published by Elsevier Inc. 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771384/ https://www.ncbi.nlm.nih.gov/pubmed/24210113 http://dx.doi.org/10.1016/j.virol.2013.09.003

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