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Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease
Increasing evidence points to defects in autophagy as a common denominator in most neurodegenerative conditions. Progressive functional decline in the autophagy-lysosomal pathway (ALP) occurs with age, and the consequent impairment in protein processing capacity has been associated with a higher ris...
Autores principales: | Matrone, Carmela, Dzamko, Nicolas, Madsen, Peder, Nyegaard, Mette, Pohlmann, Regina, Søndergaard, Rikke V., Lassen, Louise B., Andresen, Thomas L., Halliday, Glenda M., Jensen, Poul Henning, Nielsen, Morten S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979956/ https://www.ncbi.nlm.nih.gov/pubmed/27509067 http://dx.doi.org/10.1371/journal.pone.0160501 |
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