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The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia
Clostridium difficile is the most common hospital acquired pathogen in the United States, and infection is in many cases fatal. Toxins A and B are its major virulence factors, but increasingly a third toxin may be present, known as C. difficile transferase (CDT). An ADP-ribosyltransferase that cause...
Autores principales: | Cowardin, Carrie A., Buonomo, Erica L., Saleh, Mahmoud M., Wilson, Madeline G., Burgess, Stacey L., Kuehne, Sarah A., Schwan, Carsten, Eichhoff, Anna M., Koch-Nolte, Friedrich, Lyras, Dena, Aktories, Klaus, Minton, Nigel P., Petri, William A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010011/ https://www.ncbi.nlm.nih.gov/pubmed/27573114 http://dx.doi.org/10.1038/nmicrobiol.2016.108 |
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