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Laquinimod treatment in the R6/2 mouse model

The transgenic mouse model R6/2 exhibits Huntington’s disease (HD)-like deficits and basic pathophysiological similarities. We also used the pheochromocytoma-12 (PC12)-cell-line-model to investigate the effect of laquinimod on metabolic activity. Laquinimod is an orally administered immunomodulatory...

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Detalles Bibliográficos
Autores principales: Ellrichmann, Gisa, Blusch, Alina, Fatoba, Oluwaseun, Brunner, Janine, Reick, Christiane, Hayardeny, Liat, Hayden, Michael, Sehr, Dominik, Winklhofer, Konstanze F., Saft, Carsten, Gold, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504033/
https://www.ncbi.nlm.nih.gov/pubmed/28694434
http://dx.doi.org/10.1038/s41598-017-04990-1

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