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Laquinimod treatment in the R6/2 mouse model
The transgenic mouse model R6/2 exhibits Huntington’s disease (HD)-like deficits and basic pathophysiological similarities. We also used the pheochromocytoma-12 (PC12)-cell-line-model to investigate the effect of laquinimod on metabolic activity. Laquinimod is an orally administered immunomodulatory...
Autores principales: | Ellrichmann, Gisa, Blusch, Alina, Fatoba, Oluwaseun, Brunner, Janine, Reick, Christiane, Hayardeny, Liat, Hayden, Michael, Sehr, Dominik, Winklhofer, Konstanze F., Saft, Carsten, Gold, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504033/ https://www.ncbi.nlm.nih.gov/pubmed/28694434 http://dx.doi.org/10.1038/s41598-017-04990-1 |
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