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The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance
The amyloid precursor protein (APP) is a receptor-like membrane protein. Although APP processing and β-amyloid production play a central role in Alzheimer’s disease (AD) pathogenesis, the physiological function of APP remains elusive. Here, we identify APP as a novel receptor for Slit that mediates...
Autores principales: | Wang, Baiping, Li, Hongmei, Mutlu, Sena A., Bowser, Devon A., Moore, Michael J., Wang, Meng C., Zheng, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534435/ https://www.ncbi.nlm.nih.gov/pubmed/28785723 http://dx.doi.org/10.1523/ENEURO.0185-17.2017 |
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