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Whole Recombinant Saccharomyces cerevisiae Yeast Expressing Ras Mutations as Treatment for Patients With Solid Tumors Bearing Ras Mutations: Results From a Phase 1 Trial
We are developing whole, heat-killed, recombinant Saccharomyces cerevisiae yeast, engineered to encode target proteins, which stimulate immune responses against malignant cells expressing those targets. This phase 1 trial, enrolling patients with advanced colorectal or pancreas cancer, was designed...
Autores principales: | Cohn, Allen, Morse, Michael A., O’Neil, Bert, Whiting, Samuel, Coeshott, Claire, Ferraro, John, Bellgrau, Donald, Apelian, David, Rodell, Timothy C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895167/ https://www.ncbi.nlm.nih.gov/pubmed/29528991 http://dx.doi.org/10.1097/CJI.0000000000000219 |
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