Cargando…

Cell permeable HMGB1-binding heptamer peptide ameliorates neurovascular complications associated with thrombolytic therapy in rats with transient ischemic stroke

BACKGROUND: Blood–brain barrier (BBB) breakdown and inflammatory responses are the major causes of tissue-type plasminogen activator (tPA)-induced hemorrhagic transformation (HT), while high-mobility group box 1 (HMGB1) exacerbates inflammatory damage to BBB during the process of brain ischemia/repe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Miaodan, Chen, Shumin, Shi, Xue, Lyu, Chenfei, Zhang, Yongfang, Tan, Miaoqin, Wang, Chen, Zang, Nailiang, Liu, Xiaoxi, Hu, Yafang, Shen, Jiangang, Zhou, Liang, Gu, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108117/ https://www.ncbi.nlm.nih.gov/pubmed/30139371 http://dx.doi.org/10.1186/s12974-018-1267-5

Ejemplares similares

IRAK-M Deficiency Exacerbates Ischemic Neurovascular Injuries in Experimental Stroke Mice
por: Lyu, Chenfei, et al.
Publicado: (2018)

HMGB1-Binding Heptamer Confers Anti-Inflammatory Effects in Primary Microglia Culture
por: Kim, Il-Doo, et al.
Publicado: (2013)

Observation of arenavirus nucleoprotein heptamer assembly
por: Papageorgiou, Nicolas, et al.
Publicado: (2021)

The Role of Non‐Covalent Interactions on Cluster Formation: Pentamer, Hexamers and Heptamer of Difluoromethane
por: Calabrese, Camilla, et al.
Publicado: (2021)

Elastic properties of dense solid phases of hard cyclic pentamers and heptamers in two dimensions
por: Wojciechowski, K W, et al.
Publicado: (2003)

Probing the interface in a human co-chaperonin heptamer: residues disrupting oligomeric unfolded state identified
por: Guidry, Jesse J, et al.
Publicado: (2003)

HMGB1 in inflammation and cancer
por: Wang, Shumin, et al.
Publicado: (2020)

On the Catalytic Activity of the Engineered Coiled-Coil Heptamer Mimicking the Hydrolase Enzymes: Insights from a Computational Study
por: Prejanò, Mario, et al.
Publicado: (2020)

Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly
por: Xu, Xingjian, et al.
Publicado: (2020)

The heptamer sgRNA targeting the human OCT4 mRNA can upregulate the OCT4 expression
por: Nozaki, Tadasuke, et al.
Publicado: (2021)

REC domain stabilizes the active heptamer of σ(54)-dependent transcription factor, FleR from Pseudomonas aeruginosa
por: Sahoo, Pankaj Kumar, et al.
Publicado: (2023)

AMP-activated protein kinase is a key regulator of acute neurovascular permeability
por: Dragoni, Silvia, et al.
Publicado: (2021)

Neurovascular unit permeability in neuroinflammatory diseases: a common pathologic and therapeutic target?
por: Monsour, Molly, et al.
Publicado: (2022)

Consistent breakage between consensus recombinase heptamers of chromosome 9 DNA in a recurrent chromosomal translocation of human T cell leukemia
Publicado: (1989)

Non-consensus heptamer sequences destabilize the RAG post-cleavage complex, making ends available to alternative DNA repair pathways
por: Arnal, Suzzette M., et al.
Publicado: (2010)

Intranasal Delivery of RGD-Containing Osteopontin Heptamer Peptide Confers Neuroprotection in the Ischemic Brain and Augments Microglia M2 Polarization
por: Davaanyam, Dashdulam, et al.
Publicado: (2021)

Escin suppresses HMGB1‐induced overexpression of aquaporin‐1 and increased permeability in endothelial cells
por: Chen, Changjun, et al.
Publicado: (2019)

Major Determinants of Airway Epithelial Cell Sensitivity to S. aureus Alpha-Toxin: Disposal of Toxin Heptamers by Extracellular Vesicle Formation and Lysosomal Degradation
por: Möller, Nils, et al.
Publicado: (2021)

Review of Stroke Thrombolytics
por: Bivard, Andrew, et al.
Publicado: (2013)

Patching Up the Permeability: The Role of Stem Cells in Lessening Neurovascular Damage in Amyotrophic Lateral Sclerosis
por: Monsour, Molly, et al.
Publicado: (2022)

Thrombolytic Agents: Nanocarriers in Targeted Release
por: Shen, Minghua, et al.
Publicado: (2021)

Human Hsp60 with Its Mitochondrial Import Signal Occurs in Solution as Heptamers and Tetradecamers Remarkably Stable over a Wide Range of Concentrations
por: Vilasi, Silvia, et al.
Publicado: (2014)

S. aureus alpha-toxin monomer binding and heptamer formation in host cell membranes – Do they determine sensitivity of airway epithelial cells toward the toxin?
por: Möller, Nils, et al.
Publicado: (2020)

Using thrombolytics in frostbite injury
por: Gross, Eric A, et al.
Publicado: (2012)

Anticoagulant and thrombolytic therapy in surgery /
por: Malinovskiĭ, Nikolaĭ N.
Publicado: (1979)

Development and Testing of Thrombolytics in Stroke
por: Nikitin, Dmitri, et al.
Publicado: (2021)

Targeted delivery of thrombolytic enzymes
por: Kwon, Young M.
Publicado: (2021)

Outcome of Sub-Massive Pulmonary Thromboemboli in Patients Who Received Thrombolytic and or Non-Thrombolytic Therapy
por: Sadeghi, Hasan Allah, et al.
Publicado: (2016)

A Synergistic and Efficient Thrombolytic Nanoplatform: A Mechanical Method of Blasting Combined with Thrombolytic Drugs
por: Hu, Liu, et al.
Publicado: (2022)

Thrombolysis: Biological and Therapeutic Properties of New Thrombolytic Agents
por: Chen, Fabian
Publicado: (1987)

Lung‐Derived SOD3 Attenuates Neurovascular Injury After Transient Global Cerebral Ischemia
por: Mai, Nguyen, et al.
Publicado: (2019)

Evaluation of thrombolytic potential of three medicinal plants available in Bangladesh, as a potent source of thrombolytic compounds
por: Ramjan, Ali, et al.
Publicado: (2014)

In roots of Arabidopsis thaliana, the damage-associated molecular pattern AtPep1 is a stronger elicitor of immune signalling than flg22 or the chitin heptamer
por: Poncini, Lorenzo, et al.
Publicado: (2017)

HMGB1, anti-HMGB1 antibodies, and ratio of HMGB1/anti-HMGB1 antibodies as diagnosis indicator in fever of unknown origin
por: Chen, Mingkun, et al.
Publicado: (2021)

Matrine Ameliorates Colorectal Cancer in Rats via Inhibition of HMGB1 Signaling and Downregulation of IL-6, TNF-α, and HMGB1
por: Fan, Huizhen, et al.
Publicado: (2018)

Intravenous Thrombolytic Treatment in the Oldest Old
por: García-Caldentey, Juan, et al.
Publicado: (2012)

QT Dispersion after Thrombolytic Therapy
por: Oni Heris, Saeed, et al.
Publicado: (2014)

Aspect of Thrombolytic Therapy: A Review
por: Ali, Md. Ramjan, et al.
Publicado: (2014)

Structural Biology and Protein Engineering of Thrombolytics
por: Mican, Jan, et al.
Publicado: (2019)

Thrombolytic therapy in submassive pulmonary embolism
por: Özlek, Eda, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_2n9hn0k689h04apj9fcuad4g8l