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Inhibitory Effects of Diketopiperazines from Marine-Derived Streptomyces puniceus on the Isocitrate Lyase of Candida albicans
The glyoxylate cycle is a sequence of anaplerotic reactions catalyzed by the key enzymes isocitrate lyase (ICL) and malate synthase, and plays an important role in the pathogenesis of microorganisms during infection. An icl-deletion mutant of Candida albicans exhibited reduced virulence in mice comp...
Autores principales: | Kim, Heegyu, Hwang, Ji-Yeon, Shin, Jongheon, Oh, Ki-Bong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600163/ https://www.ncbi.nlm.nih.gov/pubmed/31167388 http://dx.doi.org/10.3390/molecules24112111 |
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