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Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model
OBJECTIVE: In this study, we evaluated the efficacy of simvastatin in the treatment of nonalcoholic steatohepatitis induced by methionine and choline-deficient diet in mice and its possible effect on factors involved in the pathogenesis of the disease including oxidative stress and endoplasmic retic...
Autores principales: | Rodrigues, Graziella, Moreira, Andrea Janz, Bona, Silvia, Schemitt, Elizângela, Marroni, Cláudio Augusto, Di Naso, Fábio Cangeri, Dias, Alexandre Simões, Pires, Thienne Rocha, Picada, Jaqueline Nascimento, Marroni, Norma Possa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604429/ https://www.ncbi.nlm.nih.gov/pubmed/31316716 http://dx.doi.org/10.1155/2019/3201873 |
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