Cargando…

Characterization of the Inhibitory Effect of Gastrodigenin and Gastrodin on M-type K(+) Currents in Pituitary Cells and Hippocampal Neurons

Gastrodigenin (HBA) and gastrodin (GAS) are phenolic ingredients found in Gastrodia elata Blume (GEB), a traditional Chinese herbal medicine. These compounds have been previously used to treat cognitive dysfunction, convulsion, and dizziness. However, at present, there is no available information re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Chih-Sheng, Lai, Ming-Chi, Liu, Ping-Yen, Lo, Yi-Ching, Huang, Chin-Wei, Wu, Sheng-Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982048/ https://www.ncbi.nlm.nih.gov/pubmed/31877994 http://dx.doi.org/10.3390/ijms21010117

Ejemplares similares

Novel Strategies Using Total Gastrodin and Gastrodigenin, or Total Gastrodigenin for Quality Control of Gastrodia elata
por: Tang, Chunlan, et al.
Publicado: (2018)

Gastrodin and Gastrodigenin Improve Energy Metabolism Disorders and Mitochondrial Dysfunction to Antagonize Vascular Dementia
por: Wu, Sha, et al.
Publicado: (2023)

Telmisartan, an Antagonist of Angiotensin II Receptors, Accentuates Voltage-Gated Na(+) Currents and Hippocampal Neuronal Excitability
por: Lai, Ming-Chi, et al.
Publicado: (2020)

Gastrodin Derivatives from Gastrodia elata
por: Xu, Cheng-Bo, et al.
Publicado: (2019)

Evidence for Inhibitory Effects of Flupirtine, a Centrally Acting Analgesic, on Delayed Rectifier K(+) Currents in Motor Neuron-Like Cells
por: Wu, Sheng-Nan, et al.
Publicado: (2012)

Gastrodin and Vascular Dementia: Advances and Current Perspectives
por: Deng, Chujun, et al.
Publicado: (2022)

Characterization of Inhibitory Effectiveness in Hyperpolarization-Activated Cation Currents by a Group of ent-Kaurane-Type Diterpenoids from Croton tonkinensis
por: Kuo, Ping-Chung, et al.
Publicado: (2020)

Bisoprolol, Known to Be a Selective β(1)-Receptor Antagonist, Differentially but Directly Suppresses I(K(M)) and I(K(erg)) in Pituitary Cells and Hippocampal Neurons
por: So, Edmund Cheung, et al.
Publicado: (2019)

Inhibitory control of hippocampal inhibitory neurons
por: Chamberland, Simon, et al.
Publicado: (2012)

The effects of magnetite (Fe(3)O(4)) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH(3)) cells and in RAW 264.7 macrophages
por: Liu, Yen-Chin, et al.
Publicado: (2012)

Zingerone Modulates Neuronal Voltage-Gated Na(+) and L-Type Ca(2+) Currents
por: Lai, Ming-Chi, et al.
Publicado: (2022)

Rufinamide, a Triazole-Derived Antiepileptic Drug, Stimulates Ca(2+)-Activated K(+) Currents While Inhibiting Voltage-Gated Na(+) Currents
por: Lai, Ming-Chi, et al.
Publicado: (2022)

Pioglitazone, a PPAR-γ Activator, Stimulates BK(Ca) but Suppresses IK(M) in Hippocampal Neurons
por: Chen, Tsang-Shan, et al.
Publicado: (2018)

Cannabidiol Modulates M-Type K(+) and Hyperpolarization-Activated Cation Currents
por: Liu, Yen-Chin, et al.
Publicado: (2023)

Gastrodin Protects Apoptotic Dopaminergic Neurons in a Toxin-Induced Parkinson's Disease Model
por: Kumar, Hemant, et al.
Publicado: (2013)

Clinical and economic analysis of Gastrodin injection for dizziness or vertigo: a retrospective cohort study based on electronic health records in China
por: Lai, Yunfeng, et al.
Publicado: (2022)

Effectiveness of gastrodin for migraine: A meta-analysis
por: Zhou, Xiu, et al.
Publicado: (2022)

Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson's disease model rats★
por: Li, Chun, et al.
Publicado: (2012)

Gastrodin protects dopaminergic neurons via insulin-like pathway in a Parkinson’s disease model
por: Yan, Jinyuan, et al.
Publicado: (2019)

Inhibitory effect of ultrasonic stimulation on the voltage-dependent potassium currents in rat hippocampal CA1 neurons
por: Cui, Kun, et al.
Publicado: (2019)

Evidence for Effective Inhibitory Actions on Hyperpolarization-Activated Cation Current Caused by Ganoderma Triterpenoids, the Main Active Constitutents of Ganoderma Spores
por: Chang, Wei-Ting, et al.
Publicado: (2019)

Characterization in Inhibitory Effectiveness of Carbamazepine in Voltage-Gated Na(+) and Erg-Mediated K(+) Currents in a Mouse Neural Crest-Derived (Neuro-2a) Cell Line
por: Wu, Po-Ming, et al.
Publicado: (2022)

Serotonin-mediated modulation of Na(+)/K(+ )pump current in rat hippocampal CA1 pyramidal neurons
por: Zhang, Li Nan, et al.
Publicado: (2012)

Gastrodin protects against chronic inflammatory pain by inhibiting spinal synaptic potentiation
por: Xiao, Mei-Mei, et al.
Publicado: (2016)

Clinical therapeutic effects of gastrodin in combination with betahistine on vertigo: A protocol for systematic review and meta-analysis
por: Qiao, Yu-Lin, et al.
Publicado: (2021)

A Review on Central Nervous System Effects of Gastrodin
por: Liu, Yuan, et al.
Publicado: (2018)

Role of Intestinal Microbiota in Metabolism of Gastrodin In Vitro and In Vivo
por: Nepal, Mahesh Raj, et al.
Publicado: (2019)

Mechanism and Prospect of Gastrodin in Osteoporosis, Bone Regeneration, and Osseointegration
por: Li, Yi, et al.
Publicado: (2022)

Effectiveness in the Block by Honokiol, a Dimerized Allylphenol from Magnolia Officinalis, of Hyperpolarization-Activated Cation Current and Delayed-Rectifier K(+) Current
por: Chan, Ming-Huan, et al.
Publicado: (2020)

High Effectiveness in Actions of Carfilzomib on Delayed-Rectifier K(+) Current and on Spontaneous Action Potentials
por: So, Edmund Cheung, et al.
Publicado: (2019)

Effective Activation by Kynurenic Acid and Its Aminoalkylated Derivatives on M-Type K(+) Current
por: Lo, Yi-Ching, et al.
Publicado: (2021)

Gastrodin Inhibits Store-Operated Ca(2+) Entry and Alleviates Cardiac Hypertrophy
por: Zheng, Changbo, et al.
Publicado: (2017)

Gastrodin improves learning behavior in a rat model of Alzheimer's disease induced by intra-hippocampal Aβ 1-40 injection
por: Liu, Xing, et al.
Publicado: (2012)

Gastrodin Inhibits Allodynia and Hyperalgesia in Painful Diabetic Neuropathy Rats by Decreasing Excitability of Nociceptive Primary Sensory Neurons
por: Sun, Wei, et al.
Publicado: (2012)

Intervention of Gastrodin in Type 2 Diabetes Mellitus and Its Mechanism
por: Bai, Yu, et al.
Publicado: (2021)

Comparative transcriptome analysis of Gastrodia elata (Orchidaceae) in response to fungus symbiosis to identify gastrodin biosynthesis-related genes
por: Tsai, Chi-Chu, et al.
Publicado: (2016)

Inhibitory Effectiveness in Delayed-Rectifier Potassium Current Caused by Vortioxetine, Known to Be a Novel Antidepressant
por: Hsiao, Hung-Tsung, et al.
Publicado: (2022)

Focused Ultrasound Promotes the Delivery of Gastrodin and Enhances the Protective Effect on Dopaminergic Neurons in a Mouse Model of Parkinson’s Disease
por: Wang, Yuhong, et al.
Publicado: (2022)

Differential Inhibitory Actions of Multitargeted Tyrosine Kinase Inhibitors on Different Ionic Current Types in Cardiomyocytes
por: Chang, Wei-Ting, et al.
Publicado: (2020)

Inhibitory Neuron and Hippocampal Circuit Dysfunction in an Aged Mouse Model of Alzheimer's Disease
por: Hazra, Anupam, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_q5peojuftepro4mkdplpksqp45