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Genetic feature engineering enables characterisation of shared risk factors in immune-mediated diseases
BACKGROUND: Genome-wide association studies (GWAS) have identified pervasive sharing of genetic architectures across multiple immune-mediated diseases (IMD). By learning the genetic basis of IMD risk from common diseases, this sharing can be exploited to enable analysis of less frequent IMD where, d...
Autores principales: | Burren, Oliver S., Reales, Guillermo, Wong, Limy, Bowes, John, Lee, James C., Barton, Anne, Lyons, Paul A., Smith, Kenneth G. C., Thomson, Wendy, Kirk, Paul D. W., Wallace, Chris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687775/ https://www.ncbi.nlm.nih.gov/pubmed/33239102 http://dx.doi.org/10.1186/s13073-020-00797-4 |
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