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BRN2 is a non-canonical melanoma tumor-suppressor
While the major drivers of melanoma initiation, including activation of NRAS/BRAF and loss of PTEN or CDKN2A, have been identified, the role of key transcription factors that impose altered transcriptional states in response to deregulated signaling is not well understood. The POU domain transcripti...
Autores principales: | Hamm, Michael, Sohier, Pierre, Petit, Valérie, Raymond, Jérémy H., Delmas, Véronique, Le Coz, Madeleine, Gesbert, Franck, Kenny, Colin, Aktary, Zackie, Pouteaux, Marie, Rambow, Florian, Sarasin, Alain, Charoenchon, Nisamanee, Bellacosa, Alfonso, Sanchez-del-Campo, Luis, Mosteo, Laura, Lauss, Martin, Meijer, Dies, Steingrimsson, Eirikur, Jönsson, Göran B., Cornell, Robert A., Davidson, Irwin, Goding, Colin R., Larue, Lionel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211827/ https://www.ncbi.nlm.nih.gov/pubmed/34140478 http://dx.doi.org/10.1038/s41467-021-23973-5 |
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