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Using the Cyclotide Scaffold for Targeting Biomolecular Interactions in Drug Development
This review provides an overview of the properties of cyclotides and their potential for developing novel peptide-based therapeutics. The selective disruption of protein–protein interactions remains challenging, as the interacting surfaces are relatively large and flat. However, highly constrained p...
Autores principales: | Jacob, Binu, Vogelaar, Alicia, Cadenas, Enrique, Camarero, Julio A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570680/ https://www.ncbi.nlm.nih.gov/pubmed/36234971 http://dx.doi.org/10.3390/molecules27196430 |
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