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A dsRNA-binding mutant reveals only a minor role of exonuclease activity in interferon antagonism by the arenavirus nucleoprotein
The arenavirus nucleoprotein (NP) plays an important role in the virus’ ability to block interferon (IFN) production, and its exonuclease function appears to contribute to this activity. However, efforts to analyze this contribution are complicated by the functional overlap between the exonuclease a...
Autores principales: | Bohn, Patrick, Waßmann, Irke, Wendt, Lisa, Leske, Anne, Hoenen, Thomas, Tews, Birke A., Groseth, Allison |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815661/ https://www.ncbi.nlm.nih.gov/pubmed/36603036 http://dx.doi.org/10.1371/journal.ppat.1011049 |
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