Cargando…
Integrative genetic and single cell RNA sequencing analysis provides new clues to the amyotrophic lateral sclerosis neurodegeneration
INTRODUCTION: The gradual loss of motor neurons (MNs) in the brain and spinal cord is a hallmark of amyotrophic lateral sclerosis (ALS), but the mechanisms underlying neurodegeneration in ALS are still not fully understood. METHODS: Based on 75 ALS-pathogenicity/susceptibility genes and large-scale...
Autores principales: | Liu, Hankui, Guan, Liping, Deng, Min, Bolund, Lars, Kristiansen, Karsten, Zhang, Jianguo, Luo, Yonglun, Zhang, Zhanchi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983639/ https://www.ncbi.nlm.nih.gov/pubmed/36875658 http://dx.doi.org/10.3389/fnins.2023.1116087 |
Ejemplares similares
-
Experimental models for the study of neurodegeneration in amyotrophic lateral sclerosis
por: Tovar-y-Romo, Luis B, et al.
Publicado: (2009) -
RNA-Binding Proteins in Amyotrophic Lateral Sclerosis and Neurodegeneration
por: Ugras, Scott E., et al.
Publicado: (2012) -
Epigenetic differences between monozygotic twins discordant for amyotrophic lateral sclerosis (ALS) provide clues to disease pathogenesis
por: Young, Paul E., et al.
Publicado: (2017) -
The Potential for Transition Metal-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis
por: Lovejoy, David B., et al.
Publicado: (2014) -
The Environment and Amyotrophic Lateral Sclerosis: Converging Clues from Epidemiologic Studies Worldwide
por: Vinceti, Marco
Publicado: (2012)