Effects of letrozole on serum estradiol and estrone in postmenopausal breast cancer patients and tolerability of treatment: a prospective trial using a highly sensitive LC–MS/MS (liquid chromatography–tandem mass spectrometry) method for estrogen measurement

PURPOSE: To analyze serum estradiol (E2) and estrone (E1) during letrozole treatment and their association to Quality of Life (QoL) and side-effects. METHODS: Postmenopausal breast cancer patients starting adjuvant letrozole were eligible. Serum samples were taken at baseline, three, and 12 months....

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Detalles Bibliográficos
Autores principales: Faltinová, Mária, Vehmanen, Leena, Lyytinen, Heli, Haanpää, Mikko, Hämäläinen, Esa, Tiitinen, Aila, Blomqvist, Carl, Mattson, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460747/
https://www.ncbi.nlm.nih.gov/pubmed/37491651
http://dx.doi.org/10.1007/s10549-023-07054-3

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