Validation of hypermethylated DNA regions found in colorectal cancers as potential aging-independent biomarkers of precancerous colorectal lesions

BACKGROUND: We previously identified 16,772 colorectal cancer-associated hypermethylated DNA regions that were also detectable in precancerous colorectal lesions (preCRCs) and unrelated to normal mucosal aging. We have now conducted a study to validate 990 of these differentially methylated DNA regi...

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Detalles Bibliográficos
Autores principales: Sajibu, Sija, Sonder, Emanuel, Tiwari, Amit, Orjuela, Stephany, Parker, Hannah R., Frans, Olivier The, Gubler, Christoph, Marra, Giancarlo, Robinson, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585861/
https://www.ncbi.nlm.nih.gov/pubmed/37853362
http://dx.doi.org/10.1186/s12885-023-11487-w

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