Chemical and Genetic Modulation of Complex I of the Electron Transport Chain Enhances the Biotherapeutic Protein Production Capacity of CHO Cells

Chinese hamster ovary (CHO) cells are the cell line of choice for producing recombinant therapeutic proteins. Despite improvements in production processes, reducing manufacturing costs remains a key driver in the search for more productive clones. To identify media additives capable of increasing pr...

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Detalles Bibliográficos
Autores principales: Kretzmer, Corey, Reger, Kelsey, Balassi, Vincent, Pham, Quang Long, Johns, Michael, Peters, Samuel T., Petersen, Amber, Mahadevan, Jana, Gustin, Jason, Borgschulte, Trissa, Razafsky, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670226/
https://www.ncbi.nlm.nih.gov/pubmed/37998396
http://dx.doi.org/10.3390/cells12222661

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