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When the Optimal Is Not the Best: Parameter Estimation in Complex Biological Models
BACKGROUND: The vast computational resources that became available during the past decade enabled the development and simulation of increasingly complex mathematical models of cancer growth. These models typically involve many free parameters whose determination is a substantial obstacle to model de...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963600/ https://www.ncbi.nlm.nih.gov/pubmed/21049094 http://dx.doi.org/10.1371/journal.pone.0013283 |