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BioGPS Descriptors for Rational Engineering of Enzyme Promiscuity and Structure Based Bioinformatic Analysis
A new bioinformatic methodology was developed founded on the Unsupervised Pattern Cognition Analysis of GRID-based BioGPS descriptors (Global Positioning System in Biological Space). The procedure relies entirely on three-dimensional structure analysis of enzymes and does not stem from sequence or s...
Autores principales: | Ferrario, Valerio, Siragusa, Lydia, Ebert, Cynthia, Baroni, Massimo, Foscato, Marco, Cruciani, Gabriele, Gardossi, Lucia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212942/ https://www.ncbi.nlm.nih.gov/pubmed/25353170 http://dx.doi.org/10.1371/journal.pone.0109354 |
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