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Structural basis for extracellular cis and trans RPTPσ signal competition in synaptogenesis

Receptor protein tyrosine phosphatase sigma (RPTPσ) regulates neuronal extension and acts as a presynaptic nexus for multiple protein and proteoglycan interactions during synaptogenesis. Unknown mechanisms govern the shift in RPTPσ function, from outgrowth promotion to synaptic organization. Here, w...

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Detalles Bibliográficos
Autores principales: Coles, Charlotte H., Mitakidis, Nikolaos, Zhang, Peng, Elegheert, Jonathan, Lu, Weixian, Stoker, Andrew W., Nakagawa, Terunaga, Craig, Ann Marie, Jones, E. Yvonne, Aricescu, A. Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239663/
https://www.ncbi.nlm.nih.gov/pubmed/25385546
http://dx.doi.org/10.1038/ncomms6209

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