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Sirtuins Are Evolutionarily Conserved Viral Restriction Factors

The seven human sirtuins are a family of ubiquitously expressed and evolutionarily conserved NAD(+)-dependent deacylases/mono-ADP ribosyltransferases that regulate numerous cellular and organismal functions, including metabolism, cell cycle, and longevity. Here, we report the discovery that all seve...

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Detalles Bibliográficos
Autores principales:	Koyuncu, Emre, Budayeva, Hanna G., Miteva, Yana V., Ricci, Dante P., Silhavy, Thomas J., Shenk, Thomas, Cristea, Ileana M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271551/ https://www.ncbi.nlm.nih.gov/pubmed/25516616 http://dx.doi.org/10.1128/mBio.02249-14

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