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Monoconjugation of Human Amylin with Methylpolyethyleneglycol
Amylin is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. The therapeutic restoration of postprandial and basal amylin levels is highly desirable in diabetes mellitus. Protein conjugation with the biocompatible polymer polyethylene glycol...
Autores principales: | Sisnande, Tháyna, Guerreiro, Luiz Henrique, Braga, Raquel R., Jotha-Mattos, Luana, Erthal, Luiza C. S., Tinoco, Priscilla, Ferreira, Bruno M., Lima, Luís Maurício T. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598023/ https://www.ncbi.nlm.nih.gov/pubmed/26448437 http://dx.doi.org/10.1371/journal.pone.0138803 |
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