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Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease
Common neurodegenerative proteinopathies, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), are characterized by the misfolding and aggregation of toxic protein species, including the amyloid beta (Aß) peptide, microtubule-associated protein Tau (Tau), and alpha-synuclein (αSyn) protein...
Autores principales: | Chouhan, Amit K., Guo, Caiwei, Hsieh, Yi-Chen, Ye, Hui, Senturk, Mumine, Zuo, Zhongyuan, Li, Yarong, Chatterjee, Shreyasi, Botas, Juan, Jackson, George R., Bellen, Hugo J., Shulman, Joshua M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918017/ https://www.ncbi.nlm.nih.gov/pubmed/27338814 http://dx.doi.org/10.1186/s40478-016-0333-4 |
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