Downregulation of LncRNA GAS5 causes trastuzumab resistance in breast cancer

Therapeutic resistance to trastuzumab caused by dysregulation of long noncoding RNAs (lncRNAs) is a major obstacle to clinical management of HER2-positive breast cancer. To investigate which lncRNAs contribute to trastuzumab resistance, we screened a microarray of lncRNAs involved in the malignant p...

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Detalles Bibliográficos
Autores principales: Li, Wentong, Zhai, Limin, Wang, Hui, Liu, Chuanliang, Zhang, Jinbao, Chen, Weijuan, Wei, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053687/
https://www.ncbi.nlm.nih.gov/pubmed/27034004
http://dx.doi.org/10.18632/oncotarget.8413

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