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Altered Developmental Expression of the Astrocyte-Secreted Factors Hevin and SPARC in the Fragile X Mouse Model
Astrocyte dysfunction has been indicated in many neurodevelopmental disorders, including Fragile X Syndrome (FXS). FXS is caused by a deficiency in fragile X mental retardation protein (FMRP). FMRP regulates the translation of numerous mRNAs and its loss disturbs the composition of proteins importan...
Autores principales: | Wallingford, Jessica, Scott, Angela L., Rodrigues, Kelly, Doering, Laurie C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581809/ https://www.ncbi.nlm.nih.gov/pubmed/28900386 http://dx.doi.org/10.3389/fnmol.2017.00268 |
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