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Histone deacetylase 6 inhibition rescues axonal transport impairments and prevents the neurotoxicity of HIV-1 envelope protein gp120
Despite successful antiretroviral drug therapy, a subset of human immunodeficiency virus-1 (HIV)-positive individuals still display synaptodendritic simplifications and functional cognitive impairments referred to as HIV-associated neurocognitive disorders (HANDs). The neurological damage observed i...
Autores principales: | Wenzel, Erin D., Speidell, Andrew, Flowers, Sarah A., Wu, Chengbiao, Avdoshina, Valeria, Mocchetti, Italo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742654/ https://www.ncbi.nlm.nih.gov/pubmed/31515470 http://dx.doi.org/10.1038/s41419-019-1920-7 |
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