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Pyrrothiogatain acts as an inhibitor of GATA family proteins and inhibits Th2 cell differentiation in vitro

The transcription factor GATA3 is a master regulator that modulates T helper 2 (Th2) cell differentiation and induces expression of Th2 cytokines, such as IL-4, IL-5, and IL-13. Th2 cytokines are involved in the protective immune response against foreign pathogens, such as parasites. However, excess...

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Detalles Bibliográficos
Autores principales:	Nomura, Shunsuke, Takahashi, Hirotaka, Suzuki, Junpei, Kuwahara, Makoto, Yamashita, Masakatsu, Sawasaki, Tatsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874683/ https://www.ncbi.nlm.nih.gov/pubmed/31758034 http://dx.doi.org/10.1038/s41598-019-53856-1

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