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Consistent opening of the blood brain barrier using focused ultrasound with constant intravenous infusion of microbubble agent
The blood brain barrier (BBB) is a major obstacle to the delivery of therapeutics to the brain. Focused ultrasound (FUS) in combination with microbubbles can non-invasively open the BBB in a targeted manner. Bolus intravenous injections of microbubbles are standard practice, but dynamic influx and c...
Autores principales: | Lapin, Norman A., Gill, Kirt, Shah, Bhavya R., Chopra, Rajiv |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538995/ https://www.ncbi.nlm.nih.gov/pubmed/33024157 http://dx.doi.org/10.1038/s41598-020-73312-9 |
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