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RdRp inhibitors and COVID-19: Is molnupiravir a good option?
Rapid changes in the viral genome allow viruses to evade threats posed by the host immune response or antiviral drugs, and can lead to viral persistence in the host cells. RNA-dependent RNA polymerase (RdRp) is an essential enzyme in RNA viruses, which is involved in RNA synthesis through the format...
Autores principales: | Hashemian, Seyed Mohammad Reza, Pourhanifeh, Mohammad Hossein, Hamblin, Michael R., Shahrzad, Mohammad Karim, Mirzaei, Hamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Masson SAS.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654603/ https://www.ncbi.nlm.nih.gov/pubmed/34902743 http://dx.doi.org/10.1016/j.biopha.2021.112517 |
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