Cargando…

Genome-Wide Transcriptional Response of Mycobacterium smegmatis MC(2)155 to G-Quadruplex Ligands BRACO-19 and TMPyP4

G-quadruplexes (G4s) are non-canonical DNA structures that could be considered as potential therapeutic targets for antimicrobial compounds, also known as G4-stabilizing ligands. While some of these ligands are shown in vitro to have a stabilizing effect, the precise mechanism of antibacterial actio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shitikov, Egor, Bespiatykh, Dmitry, Malakhova, Maja, Bespyatykh, Julia, Bodoev, Ivan, Vedekhina, Tatiana, Zaychikova, Marina, Veselovsky, Vladimir, Klimina, Ksenia, Ilina, Elena, Varizhuk, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931766/ https://www.ncbi.nlm.nih.gov/pubmed/35308348 http://dx.doi.org/10.3389/fmicb.2022.817024

Ejemplares similares

Bcl-2 Promoter Sequence G-Quadruplex Interactions with Three Planar and Non-Planar Cationic Porphyrins: TMPyP4, TMPyP3, and TMPyP2
por: Le, Vu H., et al.
Publicado: (2013)

Aureolic Acid Group of Agents as Potential Antituberculosis Drugs
por: Bespyatykh, Julia, et al.
Publicado: (2020)

Characterization of a G-quadruplex from hepatitis B virus and its stabilization by binding TMPyP4, BRACO19 and PhenDC3
por: Molnár, Orsolya Réka, et al.
Publicado: (2021)

Substitutions in SurA and BamA Lead to Reduced Susceptibility to Broad Range Antibiotics in Gonococci
por: Bodoev, Ivan, et al.
Publicado: (2021)

Binding of Telomestatin, TMPyP4, BSU6037, and BRACO19 to a Telomeric G-Quadruplex–Duplex Hybrid Probed by All-Atom Molecular Dynamics Simulations with Explicit Solvent
por: Sullivan, Holli-Joi, et al.
Publicado: (2018)

The Meta-Substituted Isomer of TMPyP Enables More Effective Photodynamic Bacterial Inactivation than Para-TMPyP In Vitro
por: Schulz, Sebastian, et al.
Publicado: (2022)

Metabolic Changes of Mycobacterium tuberculosis during the Anti-Tuberculosis Therapy
por: Bespyatykh, Julia, et al.
Publicado: (2020)

Pentose Phosphate Pathway Function Affects Tolerance to the G-Quadruplex Binder TMPyP4
por: Andrew, Elizabeth J., et al.
Publicado: (2013)

Author Correction: System OMICs analysis of Mycobacterium tuberculosis Beijing B0/W148 cluster
por: Bespyatykh, Julia, et al.
Publicado: (2020)

System OMICs analysis of Mycobacterium tuberculosis Beijing B0/W148 cluster
por: Bespyatykh, Julia, et al.
Publicado: (2019)

Antiviral Activity of the G-Quadruplex Ligand TMPyP4 against Herpes Simplex Virus-1
por: Artusi, Sara, et al.
Publicado: (2021)

The different biological effects of TMPyP4 and cisplatin in the inflammatory microenvironment of osteosarcoma are attributed to G‐quadruplex
por: Chen, Jianqiang, et al.
Publicado: (2021)

The Interactions of H(2)TMPyP, Analogues and Its Metal Complexes with DNA G-Quadruplexes—An Overview
por: Ramos, Catarina I. V., et al.
Publicado: (2021)

Antitumor activity of G-quadruplex-interactive agent TMPyP4 with photodynamic therapy in ovarian carcinoma cells
por: LIU, HONGLI, et al.
Publicado: (2014)

Global Transcriptomic Response of Staphylococcus aureus to Virulent Bacteriophage Infection
por: Kuptsov, Nikita, et al.
Publicado: (2022)

Stabilization of a G-Quadruplex from Unfolding by Replication Protein A Using Potassium and the Porphyrin TMPyP4
por: Prakash, Aishwarya, et al.
Publicado: (2011)

TMPyP Inhibits Amyloid-β Aggregation and Alleviates Amyloid-Induced Cytotoxicity
por: Fan, Yujuan, et al.
Publicado: (2017)

Mass spectrometric studies on effects of counter ions of TMPyP4 on binding to human telomeric DNA and RNA G-quadruplexes
por: Bai, Li-Ping, et al.
Publicado: (2014)

Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4
por: Qin, Yong, et al.
Publicado: (2007)

Transcriptomic Profile of Mycobacterium smegmatis in Response to an Imidazo[1,2-b][1,2,4,5]tetrazine Reveals Its Possible Impact on Iron Metabolism
por: Vatlin, Aleksey A., et al.
Publicado: (2021)

TMPyP4, a Stabilizer of Nucleic Acid Secondary Structure, Is a Novel Acetylcholinesterase Inhibitor
por: Fujiwara, Nana, et al.
Publicado: (2015)

TMPyP4 promotes cancer cell migration at low doses, but induces cell death at high doses
por: Zheng, Xiao-Hui, et al.
Publicado: (2016)

The quadruplex r(CGG)(n) destabilizing cationic porphyrin TMPyP4 cooperates with hnRNPs to increase the translation efficiency of fragile X premutation mRNA
por: Ofer, Noa, et al.
Publicado: (2009)

Contribution of Podoviridae and Myoviridae bacteriophages to the effectiveness of anti-staphylococcal therapeutic cocktails
por: Kornienko, Maria, et al.
Publicado: (2020)

Transcriptional Landscape of Staphylococcus aureus Kayvirus Bacteriophage vB_SauM-515A1
por: Kornienko, Maria, et al.
Publicado: (2020)

Gene Networks Underlying the Resistance of Bifidobacterium longum to Inflammatory Factors
por: Veselovsky, Vladimir A., et al.
Publicado: (2020)

The Gene Expression Profile Differs in Growth Phases of the Bifidobacterium Longum Culture
por: Veselovsky, Vladimir A., et al.
Publicado: (2022)

DNA G-Quadruplexes Contribute to CTCF Recruitment
por: Tikhonova, Polina, et al.
Publicado: (2021)

Telomerase Inhibitor TMPyP4 Alters Adhesion and Migration of Breast-Cancer Cells MCF7 and MDA-MB-231
por: Konieczna, Natalia, et al.
Publicado: (2019)

Isolation and Characterization of the First Zobellviridae Family Bacteriophage Infecting Klebsiella pneumoniae
por: Gorodnichev, Roman B., et al.
Publicado: (2023)

A Comprehensive Map of Mycobacterium tuberculosis Complex Regions of Difference
por: Bespiatykh, D., et al.
Publicado: (2021)

PCR Assay for Rapid Taxonomic Differentiation of Virulent Staphylococcus aureus and Klebsiella pneumoniae Bacteriophages
por: Kornienko, Maria, et al.
Publicado: (2023)

The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene
por: Mori, Kohji, et al.
Publicado: (2021)

Photodynamic Activity of TMPyP4/TiO(2) Complex under Blue Light in Human Melanoma Cells: Potential for Cancer-Selective Therapy
por: Balas, Mihaela, et al.
Publicado: (2023)

A revised SNP-based barcoding scheme for typing Mycobacterium tuberculosis complex isolates
por: Shitikov, Egor, et al.
Publicado: (2023)

Sensitive Hg(2+) Sensing via Quenching the Fluorescence of the Complex between Polythymine and 5,10,15,20-tetrakis(N-methyl-4-pyridyl) Porphyrin (TMPyP)
por: Wu, Daohong, et al.
Publicado: (2018)

Novel Klebsiella pneumoniae K23-Specific Bacteriophages From Different Families: Similarity of Depolymerases and Their Therapeutic Potential
por: Gorodnichev, Roman B., et al.
Publicado: (2021)

Binding of BRACO19 to a Telomeric G-Quadruplex DNA Probed by All-Atom Molecular Dynamics Simulations with Explicit Solvent
por: Machireddy, Babitha, et al.
Publicado: (2019)

Evolutionary pathway analysis and unified classification of East Asian lineage of Mycobacterium tuberculosis
por: Shitikov, Egor, et al.
Publicado: (2017)

Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells
por: Zhou, Guangtong, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1bcoep0rl27plfdlj5p7uvdb89