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VPS29 Exerts Opposing Effects on Endocytic Viral Entry

Emerging zoonotic viral pathogens threaten global health, and there is an urgent need to discover host and viral determinants influencing infection. We performed a loss-of-function genome-wide CRISPR screen in a human lung cell line using HCoV-OC43, a human betacoronavirus. One candidate gene, VPS29...

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Detalles Bibliográficos
Autores principales:	Poston, Daniel, Weisblum, Yiska, Hobbs, Alvaro, Bieniasz, Paul D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941944/ https://www.ncbi.nlm.nih.gov/pubmed/35229640 http://dx.doi.org/10.1128/mbio.03002-21

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