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Purifying selection enduringly acts on the sequence evolution of highly expressed proteins in Escherichia coli
The evolutionary speed of a protein sequence is constrained by its expression level, with highly expressed proteins evolving relatively slowly. This negative correlation between expression levels and evolutionary rates (known as the E–R anticorrelation) has already been widely observed in past macro...
Autores principales: | Shibai, Atsushi, Kotani, Hazuki, Sakata, Natsue, Furusawa, Chikara, Tsuru, Saburo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635659/ https://www.ncbi.nlm.nih.gov/pubmed/36073932 http://dx.doi.org/10.1093/g3journal/jkac235 |
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