Processing and turnover of the Hedgehog protein in the endoplasmic reticulum

The Hedgehog (Hh) signaling pathway has important functions during metazoan development. The Hh ligand is generated from a precursor by self-cleavage, which requires a free cysteine in the C-terminal part of the protein and results in the production of the cholesterol-modified ligand and a C-termina...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Tukachinsky, Hanna, Huang, Chih-Hsiang, Jao, Cindy, Chu, Yue-Ru, Tang, Hsiang-Yun, Mueller, Britta, Schulman, Sol, Rapoport, Tom A., Salic, Adrian
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051819/
https://www.ncbi.nlm.nih.gov/pubmed/21357747
http://dx.doi.org/10.1083/jcb.201008090

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