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A Mechanistic Modeling Framework for Predicting Metabolic Interactions in Complex Mixtures

Background: Computational modeling of the absorption, distribution, metabolism, and excretion of chemicals is now theoretically able to describe metabolic interactions in realistic mixtures of tens to hundreds of substances. That framework awaits validation. Objectives: Our objectives were to a) eva...

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Detalles Bibliográficos
Autores principales:	Cheng, Shu, Bois, Frederic Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Sciences 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261979/ https://www.ncbi.nlm.nih.gov/pubmed/21835728 http://dx.doi.org/10.1289/ehp.1103510

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