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Systemic IL-12 Administration Alters Hepatic Dendritic Cell Stimulation Capabilities

The liver is an immunologically unique organ containing tolerogenic dendritic cells (DC) that maintain an immunosuppressive microenvironment. Although systemic IL-12 administration can improve responses to tumors, the effects of IL-12-based treatments on DC, in particular hepatic DC, remain incomple...

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Detalles Bibliográficos
Autores principales:	Chan, Tim, Back, Timothy C., Subleski, Jeffrey J., Weiss, Jonathan M., Ortaldo, John R., Wiltrout, Robert H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302816/ https://www.ncbi.nlm.nih.gov/pubmed/22428016 http://dx.doi.org/10.1371/journal.pone.0033303

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