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Absence of PTHrP Nuclear Localization and Carboxyl Terminus Sequences Leads to Abnormal Brain Development and Function
We assessed whether the nuclear localization sequences (NLS) and C terminus of parathyroid hormone-related protein (PTHrP) play critical roles in brain development and function. We used histology, immunohistochemistry, histomorphometry, Western blots and electrophysiological recordings to compare th...
Autores principales: | Gu, Zhen, Liu, Yahong, Zhang, Yongjie, Jin, Shulei, Chen, Qi, Goltzman, David, Karaplis, Andrew, Miao, Dengshun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402381/ https://www.ncbi.nlm.nih.gov/pubmed/22844494 http://dx.doi.org/10.1371/journal.pone.0041542 |
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