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The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis
PIWI-family proteins and their associated small RNAs (piRNAs) act in an evolutionarily conserved innate immune mechanism that provides an essential protection for germ cell genomes against the activity of mobile genetic elements(1). piRNA populations comprise a molecular definition of transposons th...
Autores principales: | Ipsaro, Jonathan J., Haase, Astrid D., Knott, Simon R., Joshua-Tor, Leemor, Hannon, Gregory J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493678/ https://www.ncbi.nlm.nih.gov/pubmed/23064227 http://dx.doi.org/10.1038/nature11502 |
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