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Predicting enhancer transcription and activity from chromatin modifications

Enhancers play a pivotal role in regulating the transcription of distal genes. Although certain chromatin features, such as the histone acetyltransferase P300 and the histone modification H3K4me1, indicate the presence of enhancers, only a fraction of enhancers are functionally active. Individual ch...

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Detalles Bibliográficos
Autores principales:	Zhu, Yun, Sun, Lin, Chen, Zhao, Whitaker, John W., Wang, Tao, Wang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905895/ https://www.ncbi.nlm.nih.gov/pubmed/24038352 http://dx.doi.org/10.1093/nar/gkt826

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