Genotypic and Functional Impact of HIV-1 Adaptation to Its Host Population during the North American Epidemic

HLA-restricted immune escape mutations that persist following HIV transmission could gradually spread through the viral population, thereby compromising host antiviral immunity as the epidemic progresses. To assess the extent and phenotypic impact of this phenomenon in an immunogenetically diverse p...

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Detalles Bibliográficos
Autores principales: Cotton, Laura A., Kuang, Xiaomei T., Le, Anh Q., Carlson, Jonathan M., Chan, Benjamin, Chopera, Denis R., Brumme, Chanson J., Markle, Tristan J., Martin, Eric, Shahid, Aniqa, Anmole, Gursev, Mwimanzi, Philip, Nassab, Pauline, Penney, Kali A., Rahman, Manal A., Milloy, M.-J., Schechter, Martin T., Markowitz, Martin, Carrington, Mary, Walker, Bruce D., Wagner, Theresa, Buchbinder, Susan, Fuchs, Jonathan, Koblin, Beryl, Mayer, Kenneth H., Harrigan, P. Richard, Brockman, Mark A., Poon, Art F. Y., Brumme, Zabrina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998893/
https://www.ncbi.nlm.nih.gov/pubmed/24762668
http://dx.doi.org/10.1371/journal.pgen.1004295

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