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Identification of Mycobacterium tuberculosis BioA inhibitors by using structure-based virtual screening
BACKGROUND: 7,8-Diaminopelargonic acid synthase (BioA), an enzyme of biotin biosynthesis pathway, is a well-known promising target for anti-tubercular drug development. METHODS: In this study, structure-based virtual screening was employed against the active site of BioA to identify new chemical ent...
Autores principales: | Singh, Swati, Khare, Garima, Bahal, Ritika Kar, Ghosh, Prahlad C, Tyagi, Anil K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935190/ https://www.ncbi.nlm.nih.gov/pubmed/29750019 http://dx.doi.org/10.2147/DDDT.S144240 |
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