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Adenovirus E1A Activation Domain Regulates H3 Acetylation Affecting Varied Steps in Transcription at Different Viral Promoters

How histone acetylation promotes transcription is not clearly understood. Here, we confirm an interaction between p300 and the adenovirus 2 large E1A activation domain (AD) and map the interacting regions in E1A by observing colocalization at an integrated lacO array of fusions of LacI-mCherry to E1...

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Detalles Bibliográficos
Autores principales:	Hsu, Emily, Pennella, Mario A., Zemke, Nathan R., Eng, Carol, Berk, Arnold J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146688/ https://www.ncbi.nlm.nih.gov/pubmed/29976669 http://dx.doi.org/10.1128/JVI.00805-18

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