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Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase
Mutations in the gene encoding the protein kinase CDKL5 cause a debilitating neurodevelopmental disease termed CDKL5 disorder. The impact of these mutations on CDKL5 function is poorly understood because the substrates and cellular processes controlled by CDKL5 are unclear. Here, we describe a quant...
Autores principales: | Muñoz, Ivan M, Morgan, Michael E, Peltier, Julien, Weiland, Florian, Gregorczyk, Mateusz, Brown, Fiona CM, Macartney, Thomas, Toth, Rachel, Trost, Matthias, Rouse, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293279/ https://www.ncbi.nlm.nih.gov/pubmed/30266825 http://dx.doi.org/10.15252/embj.201899559 |
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