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Discovery of Non-Peptidic Compounds against Chagas Disease Applying Pharmacophore Guided Molecular Modelling Approaches
Chagas disease is one of the primary causes of heart diseases accounting to 50,000 lives annually and is listed as the neglected tropical disease. Because the currently available therapies have greater toxic effects with higher resistance, there is a dire need to develop new drugs to combat the dise...
Autores principales: | Rampogu, Shailima, Lee, Gihwan, Baek, Ayoung, Son, Minky, Park, Chanin, Zeb, Amir, Yoon, Sang Hwa, Park, Suhyeon, Lee, Keun Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321154/ https://www.ncbi.nlm.nih.gov/pubmed/30469538 http://dx.doi.org/10.3390/molecules23123054 |
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