Cargando…
Matrine attenuates high‐fat diet‐induced in vivo and ox‐LDL‐induced in vitro vascular injury by regulating the PKCα/eNOS and PI3K/Akt/eNOS pathways
Lipid metabolism disorders lead to vascular endothelial injury. Matrine is an alkaloid that has been used to improve obesity and diabetes and for the treatment of hepatitis B. However, its effect on lipid metabolism disorders and vascular injury is unclear. Here, we investigated the effect of matrin...
Autores principales: | Zhang, Song, Guo, Shun, Gao, Xiao‐bo, Liu, An, Jiang, Wei, Chen, Xi, Yang, Peng, Liu, Lin‐na, Shi, Lei, Zhang, Yan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433715/ https://www.ncbi.nlm.nih.gov/pubmed/30770623 http://dx.doi.org/10.1111/jcmm.14180 |
Ejemplares similares
-
PKC-Dependent Phosphorylation of eNOS at T495 Regulates eNOS Coupling and Endothelial Barrier Function in Response to G(+) -Toxins
por: Chen, Feng, et al.
Publicado: (2014) -
Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity
por: Li, Huige, et al.
Publicado: (2009) -
Ursolic acid prevents doxorubicin‐induced cardiac toxicity in mice through eNOS activation and inhibition of eNOS uncoupling
por: Mu, Haiman, et al.
Publicado: (2019) -
mTOR contributes to endothelium-dependent vasorelaxation by promoting eNOS expression and preventing eNOS uncoupling
por: Wang, Yiying, et al.
Publicado: (2022) -
Endothelial NO Production Is Mandatory for Epigallocatechin-3-Gallate–induced Vasodilation: Results From eNOS Knockout (eNOS(−/−)) Mice
por: Lorenz, Mario, et al.
Publicado: (2015)