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Approaching infinite affinity through engineering of peptide–protein interaction
Much of life’s complexity depends upon contacts between proteins with precise affinity and specificity. The successful application of engineered proteins often depends on high-stability binding to their target. In recent years, various approaches have enabled proteins to form irreversible covalent i...
Autores principales: | Keeble, Anthony H., Turkki, Paula, Stokes, Samuel, Khairil Anuar, Irsyad N. A., Rahikainen, Rolle, Hytönen, Vesa P., Howarth, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936558/ https://www.ncbi.nlm.nih.gov/pubmed/31822621 http://dx.doi.org/10.1073/pnas.1909653116 |
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