Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing Cholangitis

BACKGROUND AND AIMS: Monoacylglycerol lipase (MGL) is the last enzymatic step in triglyceride degradation, hydrolyzing monoglycerides into glycerol and fatty acids (FAs) and converting 2‐arachidonoylglycerol into arachidonic acid, thus providing ligands for nuclear receptors as key regulators of hep...

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Detalles Bibliográficos
Autores principales: Tardelli, Matteo, Bruschi, Francesca V., Fuchs, Claudia D., Claudel, Thierry, Auer, Nicole, Kunczer, Victoria, Baumgartner, Maximilian, A.H.O. Ronda, Onne, Verkade, Henk Jan, Stojakovic, Tatjana, Scharnagl, Hubert, Habib, Aida, Zimmermann, Robert, Lotersztajn, Sophie, Trauner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317927/
https://www.ncbi.nlm.nih.gov/pubmed/31505038
http://dx.doi.org/10.1002/hep.30929

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