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Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis
Super-enhancers are clusters of enhancers associated with cell lineage. They can be powerful gene-regulators and may be useful in cell-type specific viral-vector development. Here, we have screened for endothelial super-enhancers and identified an enhancer from within a cluster that conferred 5–70-f...
Autores principales: | Mushimiyimana, Isidore, Niskanen, Henri, Beter, Mustafa, Laakkonen, Johanna P, Kaikkonen, Minna U, Ylä-Herttuala, Seppo, Laham-Karam, Nihay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373076/ https://www.ncbi.nlm.nih.gov/pubmed/34320216 http://dx.doi.org/10.1093/nar/gkab633 |
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